Tamara

tamaraston

We got our first look at AT&T's LTE-powered Samsung Galaxy Note back at CES, and now it looks like a very similar-looking device will be making its way to Canada on Rogers. A blog post on Rogers' official RedBoard site reveals that the network will offer the four-button, 4G LTE version of the Note from February.

For the uninitiated, the Galaxy Note is Samsung's gigantic 5.3-inch phone/hybrid tablet, which carries a massive 1280x800 HD SuperAMOLED display, and offers stylus input through Samsung's WACOM-powered "S Pen". Like the AT&T version, Rogers' Galaxy Note apparently totes a "1.5 GHz dual-core processor" of some description. Though unconfirmed, rumors suggest this is a Qualcomm Snapdragon chip rather than the Samsung Exynos found on the international Note.

For more on the Galaxy Note, check out our review of the international version, or our hands-on coverage of the AT&T version.

Source: RedBoard

Source: http://feedproxy.google.com/~r/androidcentral/~3/abe6aaYjAZU/story01.htm

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tamaraston

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tamaraston

Republican presidential candidate, former House Speaker Newt Gingrich, speaks to media during a news conference outside the Exciting Idlewild Baptist Church, Sunday, Jan. 29, 2012, in Lutz, Fla. (AP Photo/Matt Rourke)

Republican presidential candidate, former House Speaker Newt Gingrich, with his wife Callista, campaign at The Villages, Sunday, Jan. 29, 2012, in Lady Lake, Fla. (AP Photo/Matt Rourke)

Republican presidential candidate, former House Speaker Newt Gingrich, meets with supporters during a campaign event at the The Villages, Sunday, Jan. 29, 2012, in Lady Lake, Fla. (AP Photo/Matt Rourke)

LUTZ, Fla. (AP) ? Facing the possibility of a stinging defeat, Republican presidential contender Newt Gingrich combined sharp attacks on Mitt Romney with unspoken appeals for support among the state's evangelicals on Sunday, two days before the pivotal Florida primary.

In an unusual commitment of campaign time, the former House speaker attended a pair of Baptist worship services, where he sat in a pew, accompanied by his wife, Callista, and made no remarks.

In between a morning stop at a megachurch in the Tampa area and an evening visit to a church in Jacksonville, Gingrich unleashed an attack on Romney as a "pro-abortion, pro-gun control, pro-tax increase liberal" who could not be trusted to bring conservative values to the White House.

He also drew rousing cheers from a large crowd, numbered in the thousands, at a retirement community, where a Tea Party Express bus rolled slowly behind the platform where he was speaking.

Increasingly, Gingrich has reached out to evangelicals and tea party advocates as the Florida primary approaches, touting an endorsement from campaign dropout Herman Cain as well as former Alaska Gov. Sarah Palin's recent accusation that the establishment was trying to "crucify" him.

Standing outside the First Jacksonville Baptist church as dusk fell, Kurt Kelly, chairman of Florida Faith Leaders for Newt Gingrich, said the candidate held a midweek conference call with an estimated 1,000 evangelical pastors around the state.

He said the goal of the call was to solidify support as much as possible behind Gingrich, at the expense of rival contender Rick Santorum, who is running a poor third in the pre-primary polls in the state.

In the course of the conversation, Kelly said, Gingrich "shared his faith, shared his vision and shared his past."

Kelly did not expand on his reference to Gingrich's past, although the former speaker has been married three times.

He said one of the other pastors on the call questioned Gingrich further, and the candidate "showed a contrite heart and showed true confession and true repentance."

Gingrich was anything but repentant in his remarks about Romney during the day.

During a pair of Sunday morning television interviews, he said his chief rival had adopted a "basic policy of carpet-bombing his opponent."

One of the ads being run by Romney suggests that Gingrich is exaggerating his ties to Ronald Reagan. Gingrich chafed at that, noting that the former president's son Michael was joining him on the campaign trail Monday "to prove to everybody that I am the heir to the Reagan movement, not some liberal from Massachusetts."

Cain, a tea party favorite, will also appear with Gingrich on Monday.

At a large rally Sunday at The Villages, a sprawling retirement community in central Florida, Gingrich accused Democratic President Barack Obama of coddling foreign leaders like Venezuela's Hugo Chavez and Iran's Mahmoud Ahmadinejad.

"I believe we need to be stronger than our potential enemies," Gingrich told the crowd. "The president lives in a fantasy world where there are no enemies, there are just misguided people with whom he has not yet had coffee."

He said Chavez "deliberately, cynically and insultingly gave him an anti-American book and Obama didn't have a clue that he'd been insulted."

He said the Obama administration should be focused on Ahmadinejad's "pledge to wipe out Israel and drive America out of the Middle East."

"But if I were a left-wing Harvard law graduate surrounded by really clever left-wing academics I would know that this was really a sign that (Ahmadinejad) probably had a bad childhood," Gingrich said.

He described Obama's approach to Ahmadinejad as, "If only we could unblock him we could be closer to him and we could be friends together."

Gingrich, who served in the House for two decades, also made a populist pitch as a Washington outsider. He said the GOP's "old establishment" is trying to block his path to nomination.

"It's time that someone stood up for hard-working, taxpaying Americans and said, 'Enough,'" Gingrich said. "And if that makes the old order uncomfortable, my answer is, 'Good.'"

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/89ae8247abe8493fae24405546e9a1aa/Article_2012-01-29-Gingrich/id-e5ff832d294b489d9925ee7cf3351f41

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tamaraston

Director Michel Hazanavicius arrives at the 64th Annual Directors Guild of America Awards in Los Angeles on Saturday, Jan. 28, 2012. (AP Photo/Dan Steinberg)

Director Michel Hazanavicius, right, and Berenice Bejo arrive at the 64th Annual Directors Guild of America Awards in Los Angeles on Saturday, Jan. 28, 2012. (AP Photo/Dan Steinberg)

LOS ANGELES (AP) ? The Directors Guild of America Awards are the latest Hollywood film honors to go silent.

Hollywood's top filmmakers group presented its feature-film honor Saturday to Michel Hazanavicius for his silent film "The Artist," giving him the inside track for the best-director prize at the Academy Awards.

"I really love directors. I really have respect for directors. So this is really very moving and touching for me," said Hazanavicius, whose black-and-white silent charmer has cleaned up at earlier Hollywood honors and could emerge as the best-picture favorite at the Feb. 26 Oscars.

The Directors Guild honors are one of the most-accurate forecasts for who might go on to take home an Oscar. Only six times in the 63-year history of the guild awards has the winner failed to win the Oscar for best director. And more often than not, whichever film earns the directing Oscar also wins best picture.

French filmmaker Hazanavicius, whose credits include the spy spoofs "OSS 117: Cairo, Nest of Spies" and "OSS 117: Lost in Rio," had been a virtual unknown in Hollywood until "The Artist." His throwback to early cinema centers on a silent-era star whose career crumbles when talking pictures take over in the late 1920s.

First-time nominee Hazanavicius won over a field of guild heavyweights that included past winners Martin Scorsese for "Hugo" and Woody Allen for "Midnight in Paris." Past nominees David Fincher for "The Girl with the Dragon Tattoo" and Alexander Payne for "The Descendants" also were in the running.

Accepting his nomination plaque earlier in the ceremony from his stars in "The Artist," Jean Dujardin and Berenice Bejo, Hazanavicius recalled his childhood education in great cinema, including Hollywood classics such as "Red River" and "Rio Bravo."

Hazanavicius said he felt he was being welcomed by the Directors Guild for a language they had in common: cinema.

"Maybe you noticed, but I'm French. I have an accent. I have a name that is very difficult to pronounce," Hazanavicius said. "I'm not American, and I'm not French, actually. I'm a filmmaker. ... I feel like I'm being accepted by you not as Americans but as filmmakers."

James Marsh won the film documentary prize for "Project Nim," his chronicle of the triumphs and trials of a chimpanzee that was raised like a human child. It was the latest major Hollywood prize for Marsh, who earned the documentary Academy Award for 2008's "Man on Wire."

Scorsese went zero-for-two at the guild awards. He also had been nominated for the documentary award for "George Harrison: Living in the Material World."

Robert B. Weide won the TV comedy directing award for an episode of "Curb Your Enthusiasm," while Patty Jenkins earned the TV drama prize for the pilot of "The Killing."

The award for TV movie or miniseries went to Jon Cassar for "The Kennedys."

Other television winners were:

? Reality programming: Neil P. DeGroot, "The Biggest Loser."

? Musical variety: Glenn Weiss, "The 65th Annual Tony Awards."

? Daytime serials: William Ludel, "General Hospital."

? Children's programs: Amy Schatz, "A Child's Garden of Poetry."

? Commercials: Noam Murro.

At the start of the ceremony, Guild President Taylor Hackford led the crowd in a toast to one of his predecessors, Gil Cates, the veteran producer of the Oscar broadcast who died last year.

The Directors Guild awards were the first of two major Hollywood honors this weekend. The Screen Actors Guild hands out its prizes Sunday.

___

Online:

http://www.dga.org

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/4e67281c3f754d0696fbfdee0f3f1469/Article_2012-01-29-Directors%20Awards/id-07aa80af981745cfa6c80645e30ff8ff

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tamaraston

WASHINGTON ? NBC asked GOP presidential candidate Mitt Romney on Saturday to pull a campaign advertisement made up almost entirely of a 1997 "Nightly News" report on Newt Gingrich's ethics committee reprimand.

The "History Lesson" ad started running in Florida on the weekend, when it is harder for stations to switch ad traffic even if they want to. Broadcast days before Tuesday's primary, the ad shows former NBC anchor Tom Brokaw saying that some of Gingrich's House colleagues had raised questions about the then-speaker's "future effectiveness."

Under Brokaw's image is a line that reads ? "Paid for by Romney for President, Approved by Mitt Romney."

The footage was used without permission and the extensive use of the broadcast "inaccurately suggests that NBC News and Mr. Brokaw have consented to the use of this material and agree with the political position espoused by the videos," NBC's vice president of media law, David N. Sternlicht, wrote Romney's campaign manager, Matt Rhoades.

"Aside from the obvious copyright issues, this use of the voice of Mr. Brokaw and the NBC News name exploits him and the journalistic credibility of NBC News," the letter said. The network asked for the campaign to stop running the ad immediately and revise any other videos or commercials to remove at NBC material.

"As a news organization, NBC News objects to any use of NBC News journalists and our copyrighted material that suggests to the public that we or our journalists are taking sides with any individual or organization involved in a political campaign or dispute, and we request that your organization respect that concern," the letter said.

Romney adviser Eric Fehrnstrom said the campaign isn't likely to stop running the ad.

"We just received the letter. We are reviewing it, but we believe it falls within fair use," he said. "We didn't take the entire broadcast; we just took the first 30 seconds."

NBC spokeswoman Lauren Kapp said a similar request went to other campaigns that "have inappropriately" used material from "Nightly News," "Meet the Press," "Today" and MSNBC. Kapp said she was not aware of such uses by other campaigns.

Brokaw said in a statement released by NBC that he was "extremely uncomfortable with the extended use of my personal image in this political ad. I do not want my role as a journalist compromised for political gain by any campaign."

Brokaw stepped down in 2004 after 21 years as anchor and managing editor of "Nightly News," but continues to report for the network, including on the 2012 presidential campaign.

Asked about Brokaw's concern, Fehrnstrom said only, "We respect him as a newsman who has a lot of credibility, but we believe this falls within fair use standards."

The House ethics panel investigated Gingrich's use of tax-exempt organizations. The case ended in January 1997 with a reprimand by the House and a $300,000 penalty against Gingrich for misleading the committee and prolonging its investigation.

Romney has sought the release of all records from the probe. The committee did make public its final report as well as exhibits ? which amounted to a comprehensive account of its findings. The head of the ethics committee during the Gingrich investigation, former Republican Rep. Nancy Johnson, said the committee traditionally does not publicly release investigative documents.

Source: http://us.rd.yahoo.com/dailynews/rss/gop/*http%3A//news.yahoo.com/s/ap/20120128/ap_on_el_pr/us_romney_ad

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tamaraston · January 28, 2012

I'm just not impressed with the talent this Oscar season. Perhaps I went in with too high of expectations. Perhaps I'm just heartless. Perhaps The Artist is just too similar to Singin' In the Rain: the male lead who is a spitting image of Gene Kelly, the bitchy co-star, the plucky ingenue, the new wave of talkies ousting silents, the idea to make a musical. If they were attempting homage, then there should have been some mention of real silent films of the era or even a wink at the audience when they DO borrow from the classics.The actors are amazing and have such expressive faces. The comment about Jean Dujardin looking just like Gene Kelly isn't necessarily a bad thing; he has the grace and charisma to pull off a great biopic methinks. B? (C)r? (C)nice Bejo is gorgeous and feisty. She doesn't just blow a kiss. She smacks you in the face with a kiss! "The name's Miller! Peppy Miller!"Now, my strong bias towards Singin' In the Rain isn't the main gripe I have with the film. The Artist doesn't FEEL like a "silent film," in terms of genre. It's a black and white film without sound or spoken dialogue. There aren't enough title cards to push the narrative along. George's meltdown occurs without proper set-up. The scene in which he finds all his auctioned-off memorabilia in Peppy's house is so ominously scored and so heavily littered with zooms and high/low angles, and I don't understand why. Is George and/or the audience supposed to think, "Peppy is a stalker!" or "Aww Peppy saved all his stuff" The harsh music and editing made me think the former, but neither reaction seems right. There's no reversal in him that hints at the latter; he just plows on with self-loathing. If all that cinematic sound and fury is to imply that the love of a good woman makes him feel worse about himself, title cards would have helped.Afterwards during George's exchange with the policeman (played by Marshall's dad from HIMYM! Marvin Eriksen RIP), there are, once again, no title cards that clue us in to what the policeman could have said to cement George's desire to commit suicide. Why now? A contemporary audience is expected to fill in the blanks; we've grown good at such cerebral exercises with modern movies that don't give everything away, but if The Artist is meant to be an earnest silent film and not just a clever gimmick, it doesn't fully succeed. Similar to how purist Shakespearean actors act the text, not the subtext, silent films are about content, not context. They didn't have the technology to speak, so they had title cards. It was about need, not novelty. Now, I concede that I enjoy many subtextual interpretations of Shakespeare, but for a silent film ABOUT silent film, The Artist misses the point. As a "neo-silent film," if you will, The Artist actually uses sound very well (in the dream sequence), but it doesn't use text or content very well, which makes me wonder why/how it was nominated for Best Original Screenplay too. So I guess my final review is that it's a good modern film. It's just not a very good silent film.

January 28, 2012

Source: http://www.rottentomatoes.com/m/the_artist/

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tamaraston

When Mitt Romney released his 2010 tax returns on Tuesday, the one number that probably stood out to many Americans wasn't his 14% effective tax rate or his $20 million-plus annual income. It was the $7 million he gave to charity over the last two years, including some $4.1 million to the Church of Jesus Christ of Latter-Day Saints.

Where does that money go? In addition to donating to his family's Tyler Foundation, Romney does his duty as an active LDS member. The Mormon Church requires its members to tithe 10% of their income, and Romney's contributions match that responsibility. (PHOTOS: The Rich History of Mitt Romney)

Designed to follow the Biblical mandate to feed the hungry and clothe the naked, the Mormon tithing system supports a giant welfare infrastructure. In addition to financing temple construction and missionary programs, tithing supports more than 300 employment resource centers and 80 family services offices around the world. The church employs some 8,500 missionaries who teach English, give agricultural aid, provide medical practices and distribute clothing. It even stores a 3-6 month food supply so its members won't go hungry in the event of a disaster, and most families forgo two consecutive meals a month to give money as a "fast offering" for the poor. Local bishops -- a position Romney once held -- work with members of their local church wards to overcome economic hardships, and are even empowered to pay a family's mortgage in the hardest of times.

Structured or not, these donations set Romney apart from his political colleagues. In 2010, Romney gave away 16% of his income while Newt Gingrich's returns show he gave only 2.6%. The portion Gingrich donated to his Washington D.C. home church, the Basilica of the National Shrine of the Immaculate Conception, was even smaller -- 0.3%, or $9,540. Because the Gingrichs' also reported an earned income of $5,918 from the National Shrine -- Callista sings as an alto in the church's professional choir, which pays $80 per mass and rehearsal -- so the net balance of their contributions sinks below $4,000. The rest of Gingrich's charitable donations went to unspecified cash contributions through the Gingrichs' businesses, some $68,500, and to miscellaneous donations, near $3,100. The Obamas, meanwhile, gave 14% of their income to a total of 36 different charities in 2010. Much of that went to the Fisher House Foundation, a charity that works with veterans, and smaller amounts went to the Clinton Bush Haiti Fund and the Boys and Girls Club of America. A religious body was not listed on their returns, but the Obamas have not become members of a church while living in Washington. (VIDEO: Explaining Mitt Romney's 14% Federal Tax Rate)

In Monday's debate, Romney said he is "proud of the fact that I pay a lot of taxes." Though he's at times reluctant to speak publicly about his Mormon faith, his charitable giving, half of which goes to the socially-active LDS church, is something to be proud of as well.

View this article on Time.com

Researchers at CIC BioGUNE have found a strong relationship between high levels of Hu antigen R protein and the malignancy of hepatocellular carcinoma

This release is available in Spanish.

Researchers at CIC Biogune, the Cooperative Centre for Research into Biosciences and led by Dr. Maria Luz Martinez Chantar, have found a strong relationship between high levels of Hu antigen R (HuR) protein and the malignancy of Hepatocellular Carcinoma, through a novel molecular process in the investigation of this pathology and known as neddylation. The project provides new opportunities for making advances in the quest for personalised therapeutic applications in the treatment for Hepatocarcinoma.

Hepatocellular Carcinoma (HCC) is the cause of most liver cancers, the fifth most frequent cancer worldwide and the third after lung and gastric cancers. HCC is a tumour with a poor prognosis, even in developed countries; its incidence is similar to its death rate, most patients dying within months of diagnosis, despite diagnostic and therapeutic advances. It is a highly heterogeneous tumour and so the scientific community is redoubling its efforts to establish personalised and highly specific therapeutic targets.

Researchers from the Metabolomic Unit at CIC bioGUNE and led by Dr. Martinez, have gone one step further with this type of tumour and have revealed a hitherto unknown molecular mechanism that is involved in the development of CHC, showing that the malignancy of this illness may be linked to the overexpression of the HuR protein.
The research work, published in the Hepatology journal, and which has obtained a mention in the Cancer section of the prestigious Nature Reviews Gastroenterology & Hepatology journal, showed the relation between high levels of HuR protein and the malignancy of Hepatocellular Carcinoma by means of a molecular mechanism neddylation - totally novel in these kinds of tumour and effectively opens up new opportunities for the future development of potential therapeutic applications for patients with this pathology. The route also proved to have an application in cancer of the colon, given the high correlation between both types of tumour.

"Neddylation is an enzymatic reaction which, in the biological context, avoids the degradation of the protein modified with the NEDD8 molecule. Just as the ubiquitination marks the proteins to order them to be degraded, neddylation marks them in order to stabilise them and, in theory, these proteins are important for the tumour to proliferate and develop", explained Dr Martnez, lead researcher in the project.

In this way, the strategy followed has been to maintain the HuR protein at high levels of expression through its modification by neddylation, thus encouraging its proliferation and the malignancy of the HCC, in such a way that, "when we block the neddylation action or regulate the levels of HuR protein in liver tumours and in in vitro and in vivo hepatoma lines, cell death is induced and tumour regression takes place", stated Dr Martnez.

The options of conventional oncological treatment for Hepatocellular Carcinoma are limited, given that it is a highly chemoresistant tumour, usually arising from a cirrhotic liver. Approximately 40% of the patients diagnosed with HCC are in at an advanced stage and whose short-term prognosis produces a survival rate of 1 year in 29% of cases and of 2 years in 16%. This neoplasia is a unique situation in oncology and, despite its high incidence and poor prognosis, has not had an effective therapeutic option to date. A possible explanation for this is the wide-ranging heterogeneity in the molecular mechanisms involved in the development of this tumour.

The following step in this long and complex process of research is to find a potential therapeutic application for the formula found. This is why Dr Martnez has come to an agreement with the pharmaceutical Millenium: the Takeda Oncology Company to apply new neddylation inhibitors, marketed by this company and currently being tested in other types of tumours, to in vivo Hepatocellular Carcinoma models (mice), in order to explore this new therapeutic solution.

"Now that we have discovered that neddylation can play an important role in the development and progress of HCC, the next step is to undertake an in-depth study of possible therapeutic applications", concluded Dr Martnez.

###
[ | E-mail | Share ]
?

AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.

New therapeutic target to combat liver cancer discovered Public release date: 26-Jan-2012
[ | E-mail | Share ]
Contact: Aitziber Lasa
a.lasa@elhuyar.com
34-943-363-040
Elhuyar Fundazioa

Researchers at CIC BioGUNE have found a strong relationship between high levels of Hu antigen R protein and the malignancy of hepatocellular carcinoma

This release is available in Spanish.

Researchers at CIC Biogune, the Cooperative Centre for Research into Biosciences and led by Dr. Maria Luz Martinez Chantar, have found a strong relationship between high levels of Hu antigen R (HuR) protein and the malignancy of Hepatocellular Carcinoma, through a novel molecular process in the investigation of this pathology and known as neddylation. The project provides new opportunities for making advances in the quest for personalised therapeutic applications in the treatment for Hepatocarcinoma.

Hepatocellular Carcinoma (HCC) is the cause of most liver cancers, the fifth most frequent cancer worldwide and the third after lung and gastric cancers. HCC is a tumour with a poor prognosis, even in developed countries; its incidence is similar to its death rate, most patients dying within months of diagnosis, despite diagnostic and therapeutic advances. It is a highly heterogeneous tumour and so the scientific community is redoubling its efforts to establish personalised and highly specific therapeutic targets.

Researchers from the Metabolomic Unit at CIC bioGUNE and led by Dr. Martinez, have gone one step further with this type of tumour and have revealed a hitherto unknown molecular mechanism that is involved in the development of CHC, showing that the malignancy of this illness may be linked to the overexpression of the HuR protein.
The research work, published in the Hepatology journal, and which has obtained a mention in the Cancer section of the prestigious Nature Reviews Gastroenterology & Hepatology journal, showed the relation between high levels of HuR protein and the malignancy of Hepatocellular Carcinoma by means of a molecular mechanism neddylation - totally novel in these kinds of tumour and effectively opens up new opportunities for the future development of potential therapeutic applications for patients with this pathology. The route also proved to have an application in cancer of the colon, given the high correlation between both types of tumour.

"Neddylation is an enzymatic reaction which, in the biological context, avoids the degradation of the protein modified with the NEDD8 molecule. Just as the ubiquitination marks the proteins to order them to be degraded, neddylation marks them in order to stabilise them and, in theory, these proteins are important for the tumour to proliferate and develop", explained Dr Martnez, lead researcher in the project.

In this way, the strategy followed has been to maintain the HuR protein at high levels of expression through its modification by neddylation, thus encouraging its proliferation and the malignancy of the HCC, in such a way that, "when we block the neddylation action or regulate the levels of HuR protein in liver tumours and in in vitro and in vivo hepatoma lines, cell death is induced and tumour regression takes place", stated Dr Martnez.

The options of conventional oncological treatment for Hepatocellular Carcinoma are limited, given that it is a highly chemoresistant tumour, usually arising from a cirrhotic liver. Approximately 40% of the patients diagnosed with HCC are in at an advanced stage and whose short-term prognosis produces a survival rate of 1 year in 29% of cases and of 2 years in 16%. This neoplasia is a unique situation in oncology and, despite its high incidence and poor prognosis, has not had an effective therapeutic option to date. A possible explanation for this is the wide-ranging heterogeneity in the molecular mechanisms involved in the development of this tumour.

The following step in this long and complex process of research is to find a potential therapeutic application for the formula found. This is why Dr Martnez has come to an agreement with the pharmaceutical Millenium: the Takeda Oncology Company to apply new neddylation inhibitors, marketed by this company and currently being tested in other types of tumours, to in vivo Hepatocellular Carcinoma models (mice), in order to explore this new therapeutic solution.

"Now that we have discovered that neddylation can play an important role in the development and progress of HCC, the next step is to undertake an in-depth study of possible therapeutic applications", concluded Dr Martnez.

###
[ | E-mail | Share ]
?

AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.

Source: http://www.eurekalert.org/pub_releases/2012-01/ef-ntt012612.php
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tamaraston

SAN FRANCISCO (Reuters) ? Apple Inc's quarterly results blew past Wall Street's expectations after U.S. consumers snapped up near-unprecedented numbers of iPhones and iPads, sending its shares up 8 percent into record territory.

The world's most valuable technology corporation returned to form after a rare miss in the previous quarter, assuaging investors' worries that its sheer size meant it was headed into a period of slower growth.

It sold 37.04 million iPhones - its flagship product - and 15.43 million iPad tablets, doubling from a year earlier and easily outpacing already heightened expectations for a strong holiday season. That helped swell its warchest of cash and securities to almost $100 billion - more than enough to plug December's U.S. budget deficit and level with California's 2012/13 spending plan.

The company founded by late Silicon Valley titan Steve Jobs - who died in October after a years-long battle with cancer - smashed estimates on all its results including gross margin, which came in at 44.7 percent during the quarter.

Apple reported a net profit of $13.06 billion, or $13.87 a share, handily outstripping an average Street forecast of $10.16 per share. The beat alone - by more than $3 a share, or $3.5 billion - would be a respectable sales figure for many smaller tech companies.

"Going into 2012, I expect strength of iPhone, iPod Touch and iPad should carry on into the year. Apple still has some tailwind, including opening up new retail stores and expanding its distribution channels," said Hendi Susanto at Gabelli & Co.

"I would say Apple still has many unpenetrated international markets ... Apple is still far from its saturation.

The results allayed lingering doubts about the ability of new Chief Executive Tim Cook to lead the company that Jobs built from a garage project into a global leader. This was the first full quarter for Apple without its legendary cofounder.

But the big quarter fueled Wall Street's impatience with Apple's $97.6 billion in cash and short-term and long-term marketable securities. Several analysts zeroed in on that war chest during the conference, quizzing both Cook and Chief Financial Officer Peter Oppenheimer about Apple's plans for that immense cache.

Oppenheimer said it was "actively discussing" the cash balance but didn't have anything to announce. Neither Cook nor Oppenheimer offered clues as to what the company was thinking on a possible dividend or stock buyback - a constant on investors' most-wanted lists - but hinted that Apple may invest in its supply chain or in acquisitions.

"While one might be tempted to conclude they will go on a buying spree, we think that is likely not the case," said Michael Yoshikami, CEO of YCMNET Advisors, which owns Apple shares. "We are looking for Apple to pay a one-time distribution rather than an ongoing dividend."

Apple's revenue leapt 73 percent to $46.33 billion, handily beating the average Wall Street analyst estimate of $38.91 billion, according to Thomson Reuters I/B/E/S.

Sales in the United States were particularly strong, with revenue rising 90 percent in the Americas region. Sales in Europe were up 55 percent even though the region is in the grip of a debt crisis that has pummeled consumer confidence.

MONSTER QUARTER

Shares in Apple jumped 8 percent to about $452 in extended trade following the earnings report. The stock - which set a record high of $427.75 just this month - had closed at $420.41 on the Nasdaq.

Several analysts had warned that Apple might face a rougher ride than usual in 2012.

Google Inc's Android - a free software to run smartphones, adopted heavily by Samsung Electronics, Motorola and others - is chipping away at Apple's market share. A host of tablets from Amazon.com Inc, among others, offers buyers viable alternatives.

And then there are the inherent difficulties in maintaining growth momentum. In fiscal 2011, Apple tacked on $43 billion to its revenue, which analysts likened to birthing a Fortune 500 from scratch - every year. Its market value stood just shy of $400 billion, rivaling Exxon Mobil for the title of largest U.S. corporation.

Still, some analysts said the stellar fiscal first quarter suggested such fears were premature, particularly given a 2012 pipeline that many expect to include the third iteration of the market-leading iPad and a fifth-generation iPhone that will trigger a new round of consumer mania.

"Customer demand was off the charts in the quarter," Oppenheimer told Reuters in an interview.

Average projections for sales of Apple products during the fiscal first quarter, which includes the holiday shopping season and one more week than is typical, were for roughly 31 million iPhones, 13.5 million to 14 million iPads and 5 million Mac computers.

On Tuesday, Apple also forecast results for its fiscal second quarter that were ahead of analyst estimates. It expects revenue of about $32.5 billion and diluted earnings per share of about $8.50. Wall Street had expected earnings of $8.04 per share on revenue of $32.1 billion in the fiscal second quarter.

"It sets up Apple well for the rest of the year," said Canaccord Genuity's Michael Walkley. "They are still ramping up the new geographies like the iPhone 4 in China, which they just started selling in January and we'll see in March results."

"IPhones and Siri (voice-activated software) still driving strong. An iPhone 5 for the end of the year with a new form factor and with LTE (next-generation mobile technology) will drive another set of gains in 2012," he added.

(Reporting by Poornima Gupta and Edwin Chan; Editing by Gary Hill)

Source: http://us.rd.yahoo.com/dailynews/rss/business/*http%3A//news.yahoo.com/s/nm/20120125/bs_nm/us_apple

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NEW YORK ? Navy accepted an invitation to play football in the Big East, starting in 2015.

The service academy has been a football independent since the program began in 1879. The Midshipmen have been thriving over the last decade. They played in eight straight bowl games before slipping to 5-7 this season and have won a record 10 straight games against rival Army.

"While our independent status has served Navy football well to date, Big East conference affiliation will help ensure our future scholar-athletes and athletic programs remain competitive at the highest levels for the foreseeable future," said Vice Admiral Michael Miller, superintendent of the U.S. Naval Academy.

Big East Commissioner John Marinatto was to hold a conference call Tuesday afternoon with Miller, athletic director Chet Gladchuk and football coach Ken Niumatalolo.

In December, the Big East added Boise State and San Diego State as football-only members and SMU, Houston and Central Florida in all sports. Those schools will join in 2013.

The Big East is trying to build a 12-team football conference with an eastern and western division and a league championship game. The conference is losing Pittsburgh and Syracuse to the Atlantic Coast Conference and West Virginia to the Big 12, but it's unclear when.

West Virginia filed a lawsuit against the Big East so it can join the Big 12 in 2012. The Big East sued West Virginia to make the school abide by the league's 27-month notification period, which would keep the Mountaineers in the Big East through the 2013-14 school year.

A Rhode Island judge has ordered West Virginia and the Big East to enter nonbinding mediation to resolve their competing lawsuits.

Pitt, Syracuse and the ACC have said they will not challenge the Big East bylaws.

Source: http://us.rd.yahoo.com/dailynews/rss/sports/*http%3A//news.yahoo.com/s/ap/20120124/ap_on_sp_co_ne/fbc_big_east_navy

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Despite Mountain View's efforts to the contrary, neither Google Wallet nor Offers, have yet to set the payment sector alight. That doesn't mean the search giant's throwing in the towel, as it vehemently expands the latter into five additional cities here in the United States. Residents of Charlotte, Kansas City, Milwaukee, San Antonio and Tampa will soon be able to participate in all sorts of discounted debauchery, joining bargain-hunters in the service's existing 33 locales. Those eager ought to hit the source links to begin, but before leaving, regale us with an outrageous tale involving a discount in the comments below.

Google Offers expands to five new locales, hipsters in Portland nonchalantly recall being first originally appeared on Engadget on Wed, 25 Jan 2012 01:49:00 EDT. Please see our terms for use of feeds.

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You are here: Home / Uncategorized / Automotive Outfitters Ratings in Portland Specifics

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Source: http://www.friendsofkcac.com/automotive-outfitters-ratings-in-portland-specifics/

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Angelina Jolie's red lips made a bold statement at the Globes last week, but she's not the only beauty whose makeup we coveted. Here are the step-by-step guides for three gorgeous looks.

KATE BECKINSALE WHO: Makeup Artist Molly Stern INSPIRATION: "Kate's Roberto Cavalli dress was so ethereal and magical; I wanted to keep the skin looking completely luminous and create a bit of edge with the eyes." HOW-TO: SKIN Molly began by moisturizing Kate's skin with Natura Bisse's The Cure Cream. She then primed with Hourglass Veil Mineral Primer, which creates a flawless canvas for makeup, followed by a light application of Hourglass Illusion Tinted Moisturizer in Sand. Molly loved the sheer finish of the foundation, which allowed the British beauty's gorgeous skin to shine through.

PLAY IT NOW: Access Hollywood Live: How To Get Angelina Jolie & Reese Witherspoon's Show-Stopping Golden Globe Looks!

CHEEKS Molly used the bronze tone in Hourglass Illume Creme-to-Powder Bronzer Duo in Sunset to add warmth to Kate's skin, and followed with the blush tone applied on the apples of her cheeks. She then dusted NARS Miss Liberty high on her cheekbone to add an extra glow.

EYES Molly used the bronze shade of Hourglass Visionaire Eye Shadow Duo in Gypsy as a base, and set it with NARS Galapagos Eye Shadow, smudged deep into the lid. For an extra pop of light, she dabbed CHANEL's Blazing Gold Ombr? Essential over the inner lid. Her lashes are deep and jet-black due to Hourglass Film Noir Full Spectrum Mascara, followed by Hourglass Film Noir Lash Lacquer which was painted over them for an extra kick of drama.

VIEW THE PHOTOS: Access Hollywood At The 2012 Golden Globes

LIPS Hourglass Femme Rouge Velvet Cr?me lipstick in Fresco was used as a base on Kate's lips, followed by Hourglass Extreme Sheen Lip Gloss in Imagine for a glistening sheen.

STACY KEIBLER WHO: Marina Gravani for NYX Cosmetics and KeSARI Beauty INSPIRATION: Marina complemented Stacy's stunning red Valentino gown with a neutral, effortless look to reveal her natural beauty.

HOW-TO:

VIEW THE PHOTOS: Golden Globes 2012: The Parties

FACE Stacy's skin was prepped the night before with the KeSARI Pore Minimizing Indian Clay Masque ($29.50/kesaribeauty.com). The day of the show, prior to applying makeup, Marina applied KeSARI Dark Circle Brightening Cream ($37.90/kesaribeauty.com) to the under eye area to reduce puffiness and impart a subtle glow. Next, Marina created a base using NYX Cosmetics HD Studio Photogenic Primer and HD Studio Photogenic Foundation in Sand Beige. She then used the NYX Cosmetics Stay Matte But Not Flat Powder Foundation in Soft Beige to attain a matte finish. The NYX Cosmetics Highlight & Contour Powder was then applied to define and highlight Stacy's cheekbones. To set the Highlight & Contour Powder and maintain a matte finish, Marina used the NYX Cosmetics Powder Blush in Dusty Rose over the apples of her cheeks.

EYES Marina applied the NYX Cosmetics HD Studio Photogenic Concealer Wand in Beige to the under eye area to even Stacy's skin tone. She then dotted the NYX Cosmetics Collection Noir Liquid Black Liner between Stacy's lashes to make them appear thicker. Marina applied a thin line of the NYX Cosmetics Liquid Black Liner to Stacy's top lid and then mixed the Liquid Black Liner with the NYX Cosmetics Powder Brown Liner for the lower lash. Marina then used the shimmery light beige eye shadow from the NYX Cosmetics Butt "Naked" Eyes Palette on Stacy's lids and the brown eye shadow from the palette in the crease. She finished the look with three coats of the NYX Cosmetics Le Chick Flick waterproof mascara from the Boudoir Mascara Collection. LIPS Marina created a nude lip to keep Stacy's look as effortless as possible. She used a neutral lip liner and followed with the NYX Cosmetics Xtreme Lip Cream in Natural--the perfect finish to Stacy's gorgeous feminine look.

VIEW THE PHOTOS: Golden Globes 2012: The Winners

FREIDA PINTO WHO: Makeup Artist Leslie Lopez INSPIRATION: "I really wanted to channel a young Sophia Loren and make Freida's eyes the focal point of her look."

HOW-TO: FACE Leslie gave Freida a flawless face by starting with L'Or?al Paris True Match Super-Blendable Foundation in W6 (Sun Beige).

CHEEKS She created a sun-kissed look on the cheeks with L'Or?al Paris Magic Smooth Souffl? Blush in Cherubic. EYES For Freida's eyelids, she used L'Or?al Paris Infallible Eye Shadow in Bronzed Taupe, and Iced Latte on the brow bone for an extra pop of shimmer. Leslie gave the look an extra layer of smokiness with L'Or?al Paris Voluminous Smoldering Eyeliner in black before curling her lashes and applying a few coats of L'Or?al Paris Voluminous Million Lashes Mascara in Black. LIPS To keep Freida's eyes the focus, she kept her lips on the natural side with L'Or?al Paris Infallible Le Rouge in Lingering Mocha, a soft mauve.

Source: http://us.rd.yahoo.com/dailynews/rss/entertainment/*http%3A//us.rd.yahoo.com/dailynews/external/omg_rss/rss_omg_en/news_glam_slam_makeup_mondays_gorgeous_tips192542054/44275844/*http%3A//omg.yahoo.com/news/glam-slam-makeup-mondays-gorgeous-tips-192542054.html

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News | More Science

A new analysis by open-science advocates present a 'clear refutation' of a controversial finding that appears to undermine assumptions about how essential phosphorus is for life

By Erika Check Hayden and Nature magazine ?| January 23, 2012

A scanning electron micrograph of GFAJ-1, the bacterium at the centre of the controversy. Image: Science/AAAS

A strange bacterium found in California?s Mono Lake cannot replace the phosphorus in its DNA with arsenic, according to researchers who have been trying to reproduce the results of a controversial report published in Science in 2010.

A group of scientists, led by microbiologist Rosie Redfield at the University of British Columbia in Vancouver, Canada, have posted data on Redfield's blog that, she says, present a ?clear refutation? of key findings from the paper.

?Their most striking claim was that arsenic had been incorporated into the backbone of DNA, and what we can say is that there is no arsenic in the DNA at all,? says Redfield.

But the authors of the Science paper are not retreating from their conclusions. ?We are thrilled that our results are stimulating more experiments from the community as well as ourselves,? first author Felisa Wolfe-Simon, now at the Lawrence Berkeley National Laboratory in California, wrote in an e-mail to Nature. ?We do not fully understand the key details of the website experiments and conditions. So we hope to see this work published in a peer-reviewed journal, as this is how science best proceeds.?

Open criticism
In the Science paper, Wolfe-Simon and her co-workers reported that they had found a bacterium called GFAJ-1 that can use the element arsenic in place of phosphorus in molecules essential to life (see Arsenic-eating microbe may redefine chemistry of life). This was surprising because phosphorus is thought to be essential for life, whereas arsenic is usually toxic.

But after Redfield and others raised numerous concerns (see Microbe gets toxic response), many of which were published as technical comments in Science, Redfield put the results to the test, documenting her progress on her blog to advance the cause of open science.

Redfield grew GFAJ-1 bacteria in arsenic and a very small amount of phosphorus, as had Wolfe-Simon and her colleagues. She then purified the DNA from the cells and sent it to Marshall Louis Reaves, a graduate student at Princeton University in New Jersey. Reaves used a caesium chloride gradient to separate the cells' DNA into fractions of varying densities, then used a mass spectrometer to identify the elements present in each fraction of DNA. He found no arsenic in any of the DNA.

But Redfield?s methods might leave defenders of the arsenic life hypothesis some wiggle room. For instance, Redfield was unable to grow any cells without adding a small amount of phosphorus. Because it is not clear how much phosphorus was used to grow the bacteria in the original paper, its authors could argue that Redfield's cells were not sufficiently phosphorus-starved to be forced to use arsenic in its place.

Wolfe-Simon also says she would not expect to find arsenic in DNA analysed on a caesium chloride gradient, because the arsenic-containing DNA might be so fragile that it would break apart and appear only in very faint bands separate from the bulk of the cell's DNA.

However, Redfield says that Reaves analysed all of the DNA purified on the gradient, so he would have detected any arsenic. Redfield also analysed the size of DNA from cells that had been stored for two months in her lab refrigerator. The DNA fragments from cells that had been grown with and without arsenic were similar sizes, indicating that DNA from arsenic-grown cells is not unstable.
Source: http://rss.sciam.com/click.phdo?i=8a2d5e66b7c9d68d79d1b7a07956aafa
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STATE COLLEGE, Pa. (AP) ? Students in State College are expressing concern for seriously ill former Penn State coach Joe Paterno.

Doctors say the 85-year-old legendary coach recently experienced complications from lung cancer. He has been hospitalized since Jan. 13.

Sophomore Max Spangler says he's concerned that the stress of the Penn State sex abuse scandal has compounded Paterno's condition. Paterno was fired in November amid accusations that he didn't do more to alert authorities about child sex abuse allegations against retired assistant coach Jerry Sandusky.

Spangler says, "I don't know how bad his situation is, but I hope it gets better. It's a lot of complications at his age."

Recent alum Ben Woodward says, "It has to be pretty heartbreaking to end on the note that it did, and not on his own terms."

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/386c25518f464186bf7a2ac026580ce7/Article_2012-01-21-Penn%20State-Paterno-Campus/id-cee7ef156d91433298e3e31761df613a

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Same-sex relationships are coming to the "Star Wars" universe, courtesy of video game developer BioWare and publisher Electronic Arts' new massively multiplayer online role- playing game (or "MMORPGs" or "MMOs" for short), "Star Wars: The Old Republic," and the decision is getting people talking.

MMOs are games that create immersive virtual environments in which millions of players can interact with computer-generated characters as well as characters created by fellow gamers. While this is BioWare's first MMO, the developer is known among fans for the emphasis they place on romantic relationships between characters in their single-player role-playing games. In the past, BioWare games have featured same-sex relationships between men and women, and in the case of the immensely popular sci-fi game "Mass Effect," relationships between men and women with an asexual alien.

BioWare originally announced that players and their companions in "Star Wars: The Old Republic" would only be able to experience mixed-gender romantic relationships. After many inquiries from fans asking the developer to explain the decision, earlier this week a new forum post by Stephen Reid, the senior online community manager for the game, showed up on the company's official website announcing that those fans had been heard and same-sex romance will be added to the game.

BioWare's statement explained that while the game will still launch with only male/female relationships, they will be adding same gender romance options in future updates.

"Due to the design constraints of a fully voiced MMO of this scale and size, many choices had to be made as to the launch and post-launch feature set. Same gender romances with companion characters in 'Star Wars: The Old Republic' will be a post-launch feature. Because 'The Old Republic' is an MMO, the game will live on through content expansions which allow us to include content and features that could not be included at launch, including the addition of more companion characters who will have additional romance options."

"Companion characters" are computer-controlled characters that follow player-created characters around the virtual world, aiding them as gamers maneuver through the story.

The response to BioWare's announcement has been massive. There are 326 pages of comments as of Friday afternoon on the official "Star Wars: The Old Republic" forum alone. They range from "thank you for listening to our requests" to "how dare you expose my children to this."

The game has no firm release date, only a release window of "holiday 2011." It has also already received an ESRB rating of "T for Teen," meaning the game is recommended for players 13 and older. Neither facts have stopped detractors from crying foul, such as John Nolte on the blog "Big Hollywood," who starts his post on the subject with "Say goodbye to your child's innocence," and ends with the inaccurate proclamation, "Announcing the gay relationships AFTER the game has been sold is pure bait and switch."

The game already has reportedly broken preorder records for publisher Electronic Arts.

Got a comment? There's lots of conversation on Newsarama's FACEBOOK and TWITTER!

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