Gigantic Hurricane Sandy bears down East Coast

NEW YORK CITY (Reuters) - Tens of millions of people along the U.S. East Coast girded themselves on Sunday for Hurricane Sandy, a gigantic storm forecast to assault the densely populated region with battering winds, dangerous flooding and even heavy snowfall.

Sandy, expected to come ashore late on Monday, could deliver a harsh blow to major cities in its target zone including New York, Philadelphia, Washington, Baltimore and Boston. Its center was forecast to strike New York-New Jersey area and then move inland toward Philadelphia and the rest of Pennsylvania.

The sheer size of the storm meant its effects would be felt from the mid-Atlantic states to New England. Officials warned of widespread power outages that could last for days.

In New York City, subway, bus and train service will be suspended on Sunday evening and up to 375,000 people were ordered to evacuate from low-lying areas.

President Barack Obama, speaking after a briefing at the federal government's storm response center in Washington, called Sandy a "serious and big storm" and asked residents to heed the orders of state and local authorities to protect themselves from its onslaught.

"It's a very, very large system," National Hurricane Center Director Rick Knabb said. "The storm is going to carve a pretty large swath of bad weather, both water and wind."

The storm could bring the country's financial nerve center to a standstill, although the major Wall Street exchanges said they planned to open as usual on Monday because they have alternative facilities they can use.

Worried residents in the hurricane's path packed stores, searching for generators, flashlights, batteries, food and other supplies in anticipation of power outages.

New York City schools will be shut on Monday. Other local governments also announced school closures.

Gale-force winds were already starting to buffet Virginia and could reach other parts of the mid-Atlantic coast on Sunday night. Tens of millions of people will feel its bluster for as long as two days, Knabb said.

Forecasters said Sandy was a rare, hybrid "super storm" created by an Arctic jet stream wrapping itself around a tropical storm, possibly causing up to 12 inches of rain in some areas, as well as up to 2 feet of snowfall in the Appalachian Mountains from West Virginia to Kentucky.

It could be the largest storm to hit the United States, according to the National Oceanic and Atmospheric Administration's (NOAA) website.

Sandy was already disrupting transportation systems. More than 700 flights, including international ones, were canceled on Sunday and nearly 2,500 more were canceled for Monday, FlightAware.com said.

CASINOS CLOSE

New Jersey casinos were ordered to close and state officials decided to shut bus and rail systems by early on Monday.

Governors in other states put National Guard troops on alert. "We're just asking people to be patient and be ready for a long haul. But we have a very aggressive power restoration program in place and I think we're ready," Virginia Governor Robert McDonnell told the CNN program "State of the Union."

In Washington, Obama said officials had assured him that they had all the resources they needed in place, and he stressed that "it is important for us to respond big and to respond fast" to the hurricane's onslaught.

"We're going to cut through red tape and we're not going to get bogged down in a lot of rules," said Obama, who was having to juggle both is re-election bid and his efforts to stay on top of the storm's impact just nine days before Election Day.

Sandy blew the presidential race off course, forcing Obama and Republican challenger Mitt Romney to cancel scheduled campaign stops. It fueled fears that the storm could disrupt early voting ahead of the November 6 election.

INSURERS PREPARE FOR STORM

U.S. stock exchanges and Wall Street banks were sending employees into Manhattan on Sunday to stay in hotels and co-workers' homes, as markets prepared to open for business on Monday even as Sandy brought public transportation to a halt.

Insurers also prepared for the storm's arrival, activating claims teams, staging adjusters near the locations most likely to be affected and generally getting ready to pay for a potentially huge volume of losses.

While Sandy's 75 mph winds were not overwhelming for a hurricane, its exceptional width means the winds will last as long as two days, wearing down trees, roofs and buildings and piling up rainfall and storm surge.

Hurricane-force winds extended 175 miles from the center of the asymmetrical storm, while its lesser tropical storm-force winds spanned 850 miles in diameter.

"That's gigantic," said Chris Landsea, the hurricane center's science and operations officer.

At high tide, it could bring a surge of seawater up to 11 feet above ground level to Long Island Sound and New York Harbor, forecasters said.

"Given the large wind field associated with Sandy, elevated water levels could span multiple tide cycles, resulting in repeated and extended periods of coastal and bayside flooding," the forecasters said.

Sandy was centered about 250 miles southeast of Cape Hatteras, North Carolina, or 575 miles south of New York City at midday on Sunday, the hurricane center said. It pushed seawater up over the barrier islands off North Carolina known as the Outer Banks.

"It's flooded all over the village," longtime Ocracoke Island resident Kathleen O'Neal told Reuters. "I would say between a foot and two feet of water."

Sandy was moving over the Atlantic parallel to the U.S. coast at 10 mph, but was forecast to make a tight westward turn toward the U.S. coast on Sunday night.

Sandy killed at least 66 people as it made its way through the Caribbean islands, including 51 in Haiti, mostly from flash flooding and mudslides, according to authorities.

(Additional reporting by Gene Cherry in North Carolina, Dave Warner in Philadelphia, Paul Thomasch in New York, Mary Ellen Clark and Ebong Udoma in Connecticut and Will Dunham in Washington; Writing by Jane Sutton and David Adams; Editing by Will Dunham)

Source: http://news.yahoo.com/threat-hurricane-sandy-grows-targets-east-coast-020222965.html

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Colorado teen confesses to schoolgirl killing, prosecutors say

GOLDEN, Colo. (Reuters) - A teen arrested on suspicion of kidnapping and killing a Colorado girl has confessed to the crime to investigators and will likely be charged as an adult, prosecutors said Thursday.

A judge ordered Austin Sigg, 17, held without bond during a brief hearing in a Golden, Colorado, courtroom. Sigg, appearing calm, was shackled at the legs and handcuffed.

The teenager is accused of slaying 10-year-old Jessica Ridgeway. The girl from the Denver suburb of Westminster was found dismembered in a crime that left parents in the area gripped with fear, leading them to walk or drive their children to and from school.

He is also accused of trying to abduct a woman jogger in a separate case.

In arguing to deny bail to Sigg, Jefferson County deputy district attorney Hal Sargent said at the hearing that investigators have obtained "a confession and DNA evidence."

"The evidence is overwhelming," he said.

A police custody report released on Wednesday said Sigg waived his right to counsel when investigators first spoke to him, in another indication he might have discussed the crimes.

At the court hearing, Sigg's public defender said that he did not have a criminal history prior to his arrest on Tuesday evening at his home in Westminster.

Jefferson County District Court Judge Ann Gail Meinster ordered Sigg held without bond.

Sigg's family and relatives of Jessica sat on opposite sides of the courtroom during the hearing. At one point, Sigg looked back at his mother.

After the hearing, Jefferson County District Attorney Scott Storey was asked by reporters if his office planned to prosecute Sigg as an adult. "I think that's the appropriate thing to do," he said.

Ridgeway vanished on October 5 and police later confirmed that mutilated remains discovered in a park about 10 miles from the Ridgeway home belonged to the missing girl.

Investigators had in recent days linked Jessica's killing to the attempted abduction in May of a local jogger, a 22-year-old woman. In that incident, a man placed a chemical-soaked rag over her mouth but she managed to escape.

Sigg was arrested on suspicion of kidnapping and murder in the death of Jessica, and criminal attempt to kidnap and murder in the jogger case, according to the custody report.

He is due to return to court on Tuesday, when prosecutors expect to formally file charges against him.

(Writing by Alex Dobuzinskis; Editing by Paul Thomasch and Vicki Allen)

Source: http://news.yahoo.com/colorado-teen-confesses-schoolgirl-killing-prosecutors-162938488.html

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As investors bet on election, odd trading crops up

NEW YORK (Reuters) - Money managers across the United States are avidly watching the November 6 presidential election, gaming out investing strategies in the event of a second term for Barack Obama or a first one for Mitt Romney.

Others are simply betting on the election itself. The online betting markets that offer this opportunity have been pretty consistent, with narrow odds favoring Obama.

Every so often, however, odd trading occurs as these markets are notably less liquid and active than the average stock exchange. Tuesday was one such example.

InTrade, a Dublin, Ireland-based website that allows users to play events like the elections by trading contracts on predicted outcomes, showed a rash of bets that caused the odds for the Republican challenger to spike suddenly - and then evaporate.

The betting site is one of the more popular ones and its presidential election contracts are among the most heavily traded surpasses those it offers on U.S. Supreme Court rulings and the Academy Awards.

Romney, the former governor of Massachusetts, was viewed as having slightly less than a 40 percent chance of winning on Tuesday morning, but jumped as high as 48 percent on InTrade that morning before retreating.

"A Rasmussen poll came out showing Romney's strongest ratings ever, and that caused individual buyers to push the price around in basically a real-time aggregate of sentiment," said Manoj Narang, chief executive of Tradeworx, a high-speed trading firm in Red Bank, New Jersey.

Narang added that while he had used InTrade personally, Tradeworx did not use the service in its strategy.

Rasmussen Reports, a pollster that releases daily three-day tracking polls of voters' election preferences at 9:30 am EDT (1330 GMT), said Tuesday that Romney's support had risen to 50 percent, compared with 46 percent for Obama.

Carl Wolfenden, exchange operations manager at InTrade, estimated that there were 40 Romney buyers Tuesday morning, compared with five sellers, but "once word got around on the spike, other people stepped in and the market settled a bit.

"If someone comes into the market with a lot of money, they can shake things up, but that doesn't last long. The market tends to bounce back quickly," he said.

Notably, the Obama contract did not have the inverse reaction. Obama contracts currently show odds of his re-election at about 57 percent, though his odds have waned from late September, when they exceeded 75 percent.

Stock market traders are used to knee-jerk reactions to data and news, and how initial bounces can fade. Romney futures closed at $4.54 on Tuesday but fell 6.8 percent to $4.23 on Wednesday, putting his odds at winning at about 43 percent.

Contracts on InTrade range in price between $0 and $10, with each dime representing a 1 percent chance that an event will occur. If Romney wins, his contacts will be sealed at $10, with investors who buy in now reaping $5.77 of profit per share. If he loses, shares will drop to $0.

Obama and Romney contracts each get daily volume of about 50,000 to 60,000 shares, according to Wolfenden. That's minor compared to the millions of shares traded daily on a stock like Bank of America Corp. The relatively slight volume can make it easier for individual investors to push prices around.

It's "not really a great market," said Barry Ritholtz, chief market strategist at Fusion IQ in New York, citing the "extremely thin" trading. "It's really an instant poll of polls."

Trends indicated by InTrade often shake out. The site's markets were correct on the last two presidential elections and in 2004 correctly predicted the winner in all 50 states.

On the other hand, Intrade contracts in 2006 leaned heavily in favor of Republicans retaining the Senate, only to see those contracts shift dramatically late on Election Day when it became apparent that Democrat James Webb was going to surprisingly defeat incumbent Republican George Allen in the Virginia Senate race.

Much like the stock market, longer-term trends show a more nuanced view of the asset's value.

"If people are just buying their favorite candidate to manipulate the price and create a rosy picture, the price will be unfairly low or high," Narang said. "But InTrade has a pretty extensive user base, so people with a profit motive will go in and fix the price. It isn't perfect, but it tends to even out."

(Editing by Leslie Gevirtz)

Source: http://news.yahoo.com/investors-bet-election-odd-trading-crops-224259759--sector.html

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UN Security Council backs plan for Syria truce over holiday weekend, but skepticism prevails

BEIRUT - The U.N. Security Council gave unanimous backing Wednesday to a four-day truce proposed by the international mediator for Syria to mark a major Muslim holiday after he warned that the failure of yet another cease-fire plan would only worsen the fighting.

Yet even this modest effort ? the international community's only plan for scaling back the violence ? appears doomed.

Previous cease-fire missions have failed, in part because neither Syrian President Bashar Assad nor rebels trying to topple him had an incentive to end their bloody war of attrition. Both sides believe they can still make gains on the battlefield even as they are locked in a stalemate, and neither has faith in negotiations on a political transition.

Lakhdar Brahimi, the U.N.-Arab League envoy to Syria, has proposed that both sides lay down their arms during the Muslim holiday of Eid al-Adha, which begins Friday.

The Security Council is normally divided on Syria, but Assad allies Russia and China joined other council members in endorsing the idea of a temporary truce that is meant to pave the way for talks on ending Syria's 19-month-old conflict.

The response on the ground ranged from lukewarm to downright rejection. Syrian government officials said they were still studying the idea, while Syria's political opposition said it was skeptical of the regime's promises. A rebel commander dismissed the plan as irrelevant and a radical Islamist group fighting alongside the rebels said it won't comply with any truce.

As Brahimi briefed the Security Council, the death toll since the start of the conflict in March 2011 crossed the threshold of 35,000, activists said, and more violence was reported across the country.

Two car bombs killed at least eight bus passengers in the capital Damascus and 12 regime soldiers near a military checkpoint in the north, while regime airstrikes on villages near a besieged army base killed 12 civilians, activists said. They also posted a video showing at least 13 bodies laid out Wednesday in a room in a Damascus suburb, some of them women and children. Each side blamed the other for the deaths.

Brahimi told the Security Council by video conference from Cairo that he hopes a truce will allow humanitarian aid to reach war-stricken areas and start transition talks, said U.N. diplomats who spoke on condition of anonymity because the meeting was private.

However, months of horrific bloodshed and deep distrust between the combatants make it unlikely they will embark on the path outlined by Brahimi. The Syrian opposition says it won't negotiate unless Assad resigns, something the Syrian leader refuses to do.

"The Syrian regime throughout its reign and up until now signs everything but violates everything," Haitham Maleh, a veteran Syrian opposition leader, said after he and others met with Arab League chief Nabil Elaraby in Cairo.

Maleh said there is concern the regime would exploit a cease-fire to take back rebel-held territory. The opposition will not accept any political solution that does not include Assad leaving his post, he said.

Brahimi has served as envoy since September, taking over from former U.N. chief Kofi Annan, who quit after failing to end the Syria fighting. Annan had pushed a six-point plan, including an April 12 cease-fire that was to lead to transition talks but never took hold.

Annan's successor has been blunt about the difficulty of his assignment, trying to lower expectations. He suggested Wednesday that even the holiday truce is a gamble, saying that failure could make the situation in Syria even worse, according to the U.N. diplomat.

Still, the international community has little else to offer. There is no appetite for military intervention, while harsher U.N. action against the regime has been blocked by Russia and China, two Security Council members with veto powers.

U.S. Secretary of State Hillary Rodham Clinton said she supports Brahimi's cease-fire so that "Syrians could celebrate in peace."

"We'd like to see the violence come to an end, there's no doubt about this, and we'd like to see a political transition take hold and begin. We've been calling for that for more than a year," she added.

Few of those involved in the conflict appeared ready to commit to a truce.

Abdelbaset Sieda, head of the main opposition group in exile, the Syrian National Council, said rebel fighters would hold their fire during the holiday unless attacked by regime forces. However, his group has no control over rebels fighting on the ground.

Rebel commander Zahran Aloush of the al-Islam brigade outside of Damascus said he's ignoring truce efforts. "How can I expect a cease-fire from a regime that has never given us anything, ever," he said via Skype.

The al-Qaida-linked group Jabhat al-Nusra, which fights with the rebels and has claimed a number of large suicide bombings against regime targets, said it will not lay down arms.

"There will be no truce between us and the prideful regime and shedder of the blood of Muslims," the group said in statement posted on militant websites. "We are not among those who allow the wily to trick us, nor are we ones who will accept to play these filthy games."

In Damascus, Foreign Ministry spokesman Jihad Makdessi said the truce proposal was still "being studied" by Syrian army leaders and that Syria's decision would be announced Thursday.

Russia's U.N. Ambassador Vitaly Churkin told reporters after the Security Council meeting that his country had received indications from Syria it would abide by a cease-fire.

Brahimi hasn't said how compliance would be monitored. Annan's truce plan was more comprehensive, calling for an open-ended truce, a pullback of troops and heavy weapons from urban centres and supervision by U.N. monitors.

In Wednesday's violence, 20 people were found dead in a building in the Damascus suburb of Douma, said local activist Mohammed Saeed, speaking via Skype. The dead included 10 women and four children, he said.

An amateur video posted online showed bodies scattered on the landings of a stairwell and sprawled out on tile floors. Among the bodies were those of two young boys, one with a hole in his head, and a woman. A thick stream of blood flowed from a doorway. Another video showed 13 bodies wrapped in blankets and laid out in two rows.

The videos matched activist descriptions of the event, but because Syria imposes tight restrictions on foreign journalists, their authenticity could not be independently verified.

The state-run news agency SANA quoted the Foreign Ministry as saying that 25 people were killed in Douma on Wednesday and that they were victims of a massacre carried out by "armed terrorists," the regime's term for opposition fighters.

Also Wednesday, Russia's chief military officer said Syrian rebels have acquired portable air defence missiles, including U.S.-made Stinger missiles. In remarks carried by Russian news agencies, Gen. Nikolai Makarov didn't say how many such missiles the rebels had and who supplied them.

A Syrian rebel told The Associated Press in Turkey that the insurgents obtained dozens of shoulder-fired anti-aircraft missiles, but would not say who provided them.

The Syrian opposition has urged its foreign backers to send heavy weapons, saying rebel fighters cannot break the stalemate as long as Assad can bomb them from the air. However, the Obama administration has refused to do so, saying the weapons might fall into the wrong hands and eventually be used against the U.S. and its allies.

In Washington, State Department spokeswoman Victoria Nuland denied that the U.S. has provided any Stingers to Syrian rebels. She challenged Russia to provide evidence suggesting otherwise.

___

Associated Press writers Edith M. Lederer at the United Nations, Maggie Fick in Cairo, Bradley Klapper in Washington and Vladimir Isachenkov in Moscow contributed reporting.

Source: http://news.yahoo.com/un-security-council-backs-plan-syria-truce-over-224656963.html

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Sweden: Postdoctoral Position in High Performance Computing ...

Position Description: KTH School of Computer Science and Communication (CSC) announces a postdoctoral position in Scientific Computing. KTH Computer Science and Communication is one of the most outstanding research and teaching environments in Information Technology in Sweden with activities at KTH and partly at Stockholm University. We conduct education and research in theoretical computer science, from theory building and analysis of mathematical models to algorithm construction, implementation and simulation.

The applied computer science research and education dealing with computer vision, robotics, machine learning, computational biology, neuroinformatics and neural networks, including high performance computing, visualization and speech and music communication. It also conducts applied research and training in media technology, human-computer interaction, interaction design and sustainable development.

The department for High Performance Computing and Visualization (HPCViz) was formed in 2012 to address current and emerging challenges for efficient use of large-scale computational resources, efficient and varied manipulations of massive data sets, and method and model development taking advantage of the new possibilities offered by modern computational infrastructure and the access to large data sets. The Computational Technology Laboratory (CTL) at HPCViz now opens a postdoctoral position in the area of scientific computing.

CTL research is focused on computational mathematical modeling with differential equations, and the development, analysis and implementation of general, reliable and efficient methods for the computer simulation of complex systems of high scientific and industrial importance. The core technology is adaptive finite element methods for turbulent fluid flow and multiphysics, implemented in the open source software project FEniCS. Uncertainty quantification, data assimilation and inverse problems are also areas of high interest.

Current application projects include aerodynamics and aeroacoustics of vehicles and airplanes, ocean and atmosphere modeling, and biomedical modeling of the human heart and the human voice.
The goal of the candidate is to add new expertise to the group, and to work in one or more projects.

Qualifications:

Candidates should have (or soon receive) a Ph.D. in an area related to the research focus of CTL (applied mathematics, computer science, numerical analysis, scientific computing, or similar), and demonstrate exceptional research accomplishments (or promise). Solid knowledge and experience of numerical methods for the solution of partial differential equations is a requirement, as well as good programming skills.

How to Apply:

Application shall include the following documents:
1. Curriculum vitae
2. Transcripts from university/university college
3. Brief description of why the applicant is interested in the position.
4. Names and contact information of two references.
Please observe that all material needs to be in English, apart from the official document.

Applications via email are to be sent to: Susanne Bergman, e-mail?jobs@csc.kth.se .
Write reference number in the email subject. (CV, etc should be sent as an attachment, as pdf-files.)

We also accept hard copy applications sent to:
KTH, CSC
Att. Susanne Bergman,
Lindstedtsv?gen 3, plan 4,
SE-100 44 Stockholm, Sweden

We are currently gathering information to help improve our recruitment process. We would, therefore, be very grateful if you could include an answer to the following question within your application: Where did you initially come across this job advertisement?

For More Information

Source: http://www.youngbrigades.com/postdoctoral-fellowships/sweden-postdoctoral-position-in-high-performance-computing-applied-mathematics-computer-science-numerical-analysis-scientific-computing-or-similar-areas.html

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"Spider-Man" co-writer has book deal

NEW YORK (AP) ? The "Spider-Man" saga is going from the stage to the page.

Glen Berger, co-writer of the disaster-prone "Spider-Man, Turn Off the Dark," is working on a book. "Song of Spider-Man: The Inside Story of the Most Controversial Musical in Broadway History," will come out next year, Simon & Schuster announced Tuesday. Simon & Schuster publisher Jonathan Karp said the book would be, "entomologically speaking," the "ultimate fly-on-the-wall account" of how a musical is made.

The big budget production became notorious for a series of stunt accidents during previews. The show was eventually revamped and the original director, Julie Taymor, was fired. Taymor later sued the producers, who countersued. A tentative settlement was reached over the summer.

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/4e67281c3f754d0696fbfdee0f3f1469/Article_2012-10-23-Books-Spider-Man/id-b6a38dfebc40484ebf14c351dc68d018

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Canada readying new moves to boost orphan drug access, R&D

Health Canada is shortly to send out for public consultation new proposals aimed at streamlining patients' access to orphan drugs and spurring research into the development of such treatments.

The agency says it is developing a modern framework for the designation, authorisation and monitoring of orphan drugs, with a key focus on international information-sharing and collaboration for the development and regulation of such products. "Enabling Canadian scientists and regulator to participate with trusted global counterparts will make better use of scarce resources and benefit Canadian patients," says Health Canada.

The new framework will maintain evidence requirements based on clinical trials and will be supported by greater information-sharing amongst international partners who are committed for pooling scarce resources for maximum benefit. Once authorised, treatments will continue to be closely monitoring for effectiveness and safety while in use, the agency says.

Announcing the proposals, Health Minister Leona Aglukkag also reported that Canada is set to become the first country in North and South America to launch Orphanet, a comprehensive database of information and services for rare diseases.

"Too often, Canadians dealing with rare diseases are faced with difficulties in accessing the information and medication they need," she said, and the proposed new approach "will better support the development and authorisation of drugs for rare diseases and launch of a new web portal to assist patients in finding the information and services they need."?

Currently, when an orphan drug is not available in Canada, doctors can apply individually for each patient through Health Canada's Special Access Programme (CAP). While facilitating access, CAP also represents a significant burden to the healthcare system, and a regulatory framework designed and used specifically to approve drugs to treat small, vulnerable populations will more effectively address this need, say government officials.

Based on existing international experience and knowledge, the new framework will provide Health Canada with new tools to gather and share information, including the registration of clinical trials. It will also facilitate patient participation in this highly-specialised area, they add.

The plans have been welcomed by the Canadian Organization for Rare Disorders (CORD), which points out that they would reverse a 16-year-old Health Canada policy "denying the need for an orphan drug policy in Canada." The moves also come nearly 30 years after the US passed the world's first orphan drug act and 12 years after the European Union (EU) did for the same for its 27 member states.

In the decade before 1980, there were only 10 new drugs for rare diseases but, since the 1983 US legislation, there have been more than 300 such treatments. However, until now, Canada's 2.8 million people with rare disorders have had access to only about half of these, and usually several years later, says CORD.

Moreover, most Canadian provinces and the Common Drug Review (CDR) - the pan-Canadian process for reviewing the clinical, cost-effectiveness and patient evidence for drugs conducted by the Canadian Agency for Drugs and Technologies in Health (CADTH) - routinely deny funding for drugs for rare diseases, even after they are approved by Health Canada, it says. Ontario, British Columbia and Alberta do have "special pathways" for rare-disease drugs but there is no consistency, so patients in one province may receive treatment while their relatives in another province will be denied, says the group, which calls instead for something similar to the "risk-pooling" scheme announced by private drug plans earlier this year that will significantly benefit patients with rare diseases and others requiring high-cost innovative therapies.

"Canada has the scientists, the clinical expertise, the industry support and the patient community to become a leader in research, drug development and treatment for rare diseases," said CORD treasury Stephen McElroy.?

"Canada may be a bit late to the party, but we are dressed and ready for action," he added.?

The views expressed in the following comments are not those of PharmaTimes or any connected third party and belong specifically to the individual who made that comment. We accept no liability for the comments made and always advise users to exercise caution.

Source: http://www.pharmatimes.com/Article/12-10-24/Canada_readying_new_moves_to_boost_orphan_drug_access_R_D.aspx

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